本科生课程：

细胞生物学

国自然青年项目、博士后面上项目以及两项横向项目

研究论文

Yu F* #, Yang S#, Ni H, Heng D, Wu X, Pei Y, An D, Li D, Liu L, Pan L, Chen Q, Zhu X, Zhou J*. O-GlcNAcylation regulates centrosome behavior and cell polarity to reduce pulmonary fibrosis and maintain the epithelial phenotype, Advanced Science, 2023, 10(36)（IF=17.521）

Yu F, Guo S, Li T, Ran J, Zhao W, Li D, Liu M, Yan X, Yang X, Zhu X, Zhou J*. Ciliary defects caused by dysregulation of O-GlcNAc modification are associated with diabetic complications, Cell Research, 2019, 29(2):171-173. （IF=46.297）

Yu F#, Zhang Q#, Liu H, Liu J, Yang S, Luo X, Liu W, Zheng H, Liu Q, Cui Y, Chen G, Li Y, Huang X, Yan X, Zhou J*, Chen Q*. Dynamic O-GlcNAcylation coordinates ferritinophagy and mitophagy to activate ferroptosis, Cell Discovery, 2022, 8(1):40. （IF=38.090）

Zheng X, Xing Y, Sun K, Jin H*, Zhao W*, Yu F*. Combination therapy with resveratrol and celastrol using folic acid-functionalized exosomes enhances the therapeutic efficacy of sepsis, Advanced Healthcare Materials, 2023, 12(29) （IF=11.092）

Zheng X, Sun K, Liu Y, Yin X, Zhu H, Yu F*, Zhao W*. Resveratrol-loaded macrophage exosomes alleviate multiple sclerosis through targeting microglia, Journal of Controlled Release, 2023, 353:675-684. （ IF=11.467）

Yang S, Liu H, Ni H, Jiang L, Yang M, Chen Q, Zhou J*, Yu F*. O-GlcNAcylation regulates phagocytosis by promoting Ezrin localization at the cell cortex, Journal of Genetics and Genomics, 2023, 50(7). （IF=5.723）

Wang K, Zhang T, Liu M, Wang D, Zhu H, Wang Z, Yu F*, Liu Y*, Zhao W*, Synthesis and immunological evaluation of Mincle ligands-based antitumor vaccines, Chinese Chemical Letters, 2022（IF=8.455）

Zhu H, Wang K, Wang Z, Wang D, Yin X, Liu Y*, Yu F*, Zhao W*. An efficient and safe MUC1-dendritic cell-derived exosome conjugate vaccine elicits potent cellular and humoral immunity and tumor inhibition in vivo, Acta Biomaterialia, 2022, 138:491-504. （IF=10.633）

Yu F, Li T, Sui Y, Chen Q, Yang S, Yang J, Hong R, Li D, Yan X, Zhao W, Zhu X, Zhou J*. O-GlcNAc transferase regulates centriole behavior and intraflagellar transport to promote ciliogenesis, Protein & Cell, 2020, 11(11):852-857. （IF=21.100）

Guo Y, Zhang H, Yan C, Shen B, Zhang Y, Guo X, Sun S, Yu F, Yan J, Liu R, Zhang Q, Zhang D, Liu H, Liu Y, Zhang Y, Li W, Qin J, Lv H, Wang Z, Yuan Y, Yang J, Zhong Y, Gao S, Hu J, Chen Q. Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction, Nature Chemical Biology, 2023, 19(4):1-10.

Ran J, Li H, Zhang Y, Yu F, Yang Y, Nie C, Yang S, Li D, Zhou J, Liu M. A non-mitotic role for Eg5 in regulating cilium formation and sonic hedgehog signaling, Science Bulletin, 2021, 66(16):1620-1623.

Yang Y, Chen M, Li J, Hong R, Yang J, Yu F, Li T, Yang S, Ran J, Guo C, Zhao Y, Luan Y, Liu M, Li D, Xie S, Zhou J. A cilium-independent role for intraflagellar transport 88 in regulating angiogenesis, Science Bulletin, 2021, 66(7):727-739.

Liu Y, Wang Z, Yu F, Li M, Zhu H, Wang K, Meng M, Zhao W. The Adjuvant of a-Galactosylceramide Presented by Gold Nanoparticles Enhances Antitumor Immune Responses of MUC1 Antigen-Based Tumor Vaccines, International Journal of Nanomedicine, 2021, 16:403-420.

Ran J, Liu M, Feng J, Li H, Ma H, Song T, Cao Y, Zhou P, Wu Y, Yang Y, Yang Y, Yu F, Guo H, Zhang L, Xie S, Li D, Gao J, Zhang X, Zhu X, Zhou J. ASK1-Mediated Phosphorylation Blocks HDAC6 Ubiquitination and Degradation to Drive the Disassembly of Photoreceptor Connecting Cilia, Developmental Cell, 2020, 53(3):287-299.

Li M, Wang Z, Yan B, Yin X, Zhao Y, Yu F, Meng M, Liu Y, Zhao W. Design of a MUC1-based tricomponent vaccine adjuvanted with FSL-1 for cancer immunotherapy, MedChemComm, 2019, 10(12):2073-2077.

Li M, Yu F, Yao C, Wang PG, Liu Y, Zhao W. Synthetic and immunological studies on trimeric MUC1 immunodominant motif antigen-based anti-cancer vaccine candidates, Organic & Biomolecular Chemistry, 2018, 16(6):993-999.

Liu Y, Wang Y, Yu F, Zhang Z, Yang Z, Zhang W, Wang PG, Zhao W. Potentiating the immune response of MUC1-based antitumor vaccines using a peptide-based nanovector as a promising vaccine adjuvant, Chemical Communications, 2017, 53(68):9486-9489.

Qin J, Yang Y, Gao S, Liu Y, Yu F, Zhou Y, Lyu R, Liu M, Liu X, Li D, Zhou J. Deregulated ALG-2/HEBP2 axis alters microtubule dynamics and mitotic spindle behavior to stimulate cancer development, Journal of Cellular Physiology, 2017, 232(11):3067-3076.

Liu Y, Zhang W, He Q, Yu F, Song T, Liu T, Zhang Z, Zhou J, Wang PG, Zhao W. Fully synthetic self-adjuvanting MUC1-fibroblast stimulating lipopeptide 1 conjugates as potential cancer vaccines, Chemical Communications, 2016, 52(72):10886-9.

发表综述

Jin H, Li M, Tian F, Yu F*, Zhao W*. An Overview of Antitumour Activity of Polysaccharides, Molecules, 2022, 27(22):8083. （IF=4.927）

Sun K, Zheng X, Jin H*, Yu F*，Zhao W. Exosomes as CNS Drug Delivery Tools and Their Applications, Pharmaceutics, 2022, 14(10):2252. （IF=6.525）

Zang L, Zhu H, Wang K, Liu Y*, Yu F*, Zhao W. Not Just Anticoagulation-New and Old Applications of Heparin, Molecules, 2022, 27(20):6968. （IF=4.927）

Yu F, Ran J, Zhou J*. Ciliopathies: Does HDAC6 Represent a New Therapeutic Target? Trends in Pharmacological Sciences, 2016, 37(2):114-119. （IF=17.638）